While the report actually runs, which takes about 15-20 minutes, amuse yourself by watching the video about how to download, read and understand your results. rs8176746 (A;C) and rs8176747 (C;G) suggests you are not type-B. An Introduction to Your Promethease Report. The world’s largest GI biobank—with corresponding longitudinal clinical records —to identify novel drug targets for treating GI patients In Greek mythology, Prometheus molded humanity out of clay and gave humanity fire to start their technological advancement. Biomedical researchers, healthcare practitioners, and customers of DNA testing services such as 23andMe and AncestryDNA use Promethease to retrieve information published about their DNA variations. @media (max-width: 479px) { } Somebody with OO blood can't make working versions of the enzymes that cap the sugar chains with piece A or B at all, so the chains are left in their "precursor" form. If so, why is it telling me that I'm probA? height: 50px; Can I upload a PDF or a DOC file that I received from my genomics provider? However, determination of blood group type can be via genosets is shown in this spreadsheet or this more complicated and comprehensive one. Reports. You're right, the rs16879498 is another (disease state track) that doesn't relate to blood type. 1020×676 62.4 KB Then, it allows you the tools to research the scientific papers which have reported results about specific variants you carry. Instead they “genotype.” While full genome sequencing looks at all your genes, genotyping analyzes the most studied gene… We reviewed my most recent blood work collected on 8/16/2012. Promethias is asking you IF you are type O, but they suggest you are most probably type A, as you carry BOTH alleles. Or you could write a blog, like me! style. Do you accept data files from tellmeGen? .myheritage_health_ad_container .myheritage_ad_desktop { @media (min-width: 480px) { This data is based on locations in your genome called single nucleotide … If you have the gene for type A blood, your body makes an enzyme that caps the sugar chains with a type A sugar piece. width: 300px; Promethease generates a report using genetic information found on SNPedia. A new genetic study has added more evidence to a decades-old association between blood type and the risk for pancreatic cancer. Looks like you're using new Reddit on an old browser. The simplified Promethease report sources content from your Promethease report and organizes it in a topical, concise, easily readable and printable table format. with hepatorenal syndrome type I were excluded sinc e in our. So I went to Promthease, and it shows: ABO blood type unknown. Press question mark to learn the rest of the keyboard shortcuts. Prometheus 360™ Precision Medicines Platform. How can I delete it? style. If you go on your report in the the top left corner, there are three tabs Main, Blood, and PGx. Your interest in this may arise if you have children with a partner that also is rs16879498 C;T, as you might expect some progeny with serioushemolytic issues. Promethease is a literature retrieval system that builds a personal DNA report based on connecting a file of DNA genotypes to the scientific findings cited in SNPedia. } Wikipedia Three common alleles (A, B and O) of the ABO gene yield the six common combinations that a person can have, each of them resulting in a particular ABO blood type (as determined serologically): SNPs in the ABO gene determine the alleles present and thereby predict ABO blood group type. That was a relief to me, as I always wonder what I’m missing by making one selection over another. Have questions? Can I upload a BAM file? Columns four and five contain the two alleles observed at this SNP (genotype). I have gs129 and it is confirmed that I'm B+, B/O. } Their reporting uses SNPedia, a website that collects research on genetic variants that put a person at high risk for certain diseases. People with type AB blood have both versions working, so they have both type A and type B pieces attached to all the sugar chains on their red blood cells, as far as the ABO blood group is concerned. Promethias is asking you IF you are type O, but they suggest you are most probably type A, as you carry BOTH alleles. If you have a type O gene, your body doesn't make functional versions of these enzymes, so they can't cap the sugar chains with anything. Minimum: 2 mL serum collected in a red-top tube(no gel) --and--5 mL whole blood collected in an EDTA (lavender-top) tube --- cariaso 02:12, 20 February 2014 (UTC) Oddly enough, I don't get Gs129. With the use of your raw data file downloaded from a DNA testing company, such as 23andMe. The results are pages of information. So you're effectively type A, the same as somebody who has AA blood. Posted on May 13, 2018 May 31, 2018. of ongoing infection. Promethease is “a literature retrieval system that builds a personal DNA report based on connecting a file of DNA genotypes to the scientific findings cited in SNPedia.” In fact, Promethease is a computer program built by SNPedia for scientific research. The following are also SNPs in the ABO gene, used only to distinguish rare variants or to predict SNPs from the above list (based on linkage): i4001527 or rs590787 are relevant to Rh+ or Rh-. Yes, Promethease has Cystic Fibrosis analysis of your data. The ABO blood group system is the best known blood typing system, determining blood group type as A, B, AB, or O, and thereby of importance for blood donors and recipients. Promethease. A Promethease Report lists some basic information in a "header" at the top. MyHeritage, Ancestry.com, and Sequencing.com, Promethease DNA analyzes it against genetic information collected by research institutions worldwide. I uploaded the wrong file. Show all. Simply upload your file and pay $12 to get a full report! When will Promethease be able to process raw data from the new GSA chips? .myheritage_ad_mobile img, Commercial users may request a license by contacting us. Show all. I recently uploaded my 23andMe raw DNA to Prometheus since it's free now. You're right, the rs16879498 is another (disease state track) that doesn't relate to blood type. Wikipedia Three common alleles (A, B and O) of the ABO gene yield the six common combinations that a person can have, each of them resulting in a particular ABO blood type (as determined serologically): You can search genes/variants/diseases as you would in Wikipedia. The ABO blood group system is the best known blood typing system, determining blood group type as A, B, AB, or O, and thereby of importance for blood donors and recipients. New comments cannot be posted and votes cannot be cast, More posts from the promethease community. Your red blood cells are covered in little sugar chains that act as tags for the immune system. The first two lines show the version of Promethease that was run (e.g., Version 0.1.161) and a time stamp when the report was generated. The genotype is reported on the forward (+) strand with respect to the human reference. Promethease.com or Promethease DNA brings the world of genomics to your fingertips. Additionally, while googling around to figure it out I came across an old reddit thread where someone suggested checking out your RHAG gene. Tag: promethease.com. SNPs in this gene determine whether an individual is of blood group type A, B, AB, or O. [/vc_column_text][vc_column_text]In the Simplified Promethease report, all health category-related information is organized into a printable table. I had been impressed to learn from the instructional video that Promethease would use After agreeing to the statements I uploaded two files; a 15 MB TXT file from 23andMe (this took less than a minute) and a 4 GB zipped VCF file from Full Genomes (which took about 40 minutes). overflow: hidden; You can use the Promethease site to search through scientific publications related to your DNA data. .myheritage_ad_mobile ins { I was curious about my blood type since I don't know it. Genetic Screenings can give guidance about potential medication adverse reactions. Even though you have the gene for type O, it's overridden by the type A one that caps all your sugar chains anyway. Click on Blood and you’ll see a large text saying “ABO blood type” with your type listed right below. (An individual with type BO blood would be B for the same reason you're type A with AO blood.) Biomedical researchers, healthcare practitioners and customers of DNA testing services (such as 23andMe , Ancestry.com , FamilyTreeDNA , Genos , etc.) I did so, and it's rs16879498(C;T), which appears to be very uncommon. As the name denotes, Ancestry.com is more focused on family lineage, whereas 23andme places a greater emphasis on health and wellness. Likewise, a Promethease report compiles all of the genetic variants found in your genetic data. Both 23andme and Ancestry offer up a limited subset of genes for their customers. Promethease is a third-party DNA testing service that provides detailed health reports on your risk of developing certain diseases based on your genetic profile. (Only people with OO blood are actually type O, since AO gets overridden by the A and BO gets overridden by the B.) The Different Blood Types. I think until we have phased data, calling blood type remains impossible for some of the hard cases. Managing account & files How can I download my report to view it offline? However, it is important to realize that neither provider offers full genome sequencing. Promethease is a wiki-style collection of peer curated genetic information versus reports that are expert-curated (like Xcode Life's reports). Promethease DNA Analysis Reports Promethease is a literature retrieval system that builds a personal DNA report based on connecting a file of DNA genotypes to the scientific findings. For the pu rpose of this study, patients. .myheritage_health_ad_container .myheritage_ad_mobile { rs8176719 (I;D) rs8176746 (A;C) rs8176747 (C;G) rs8176719 (I;D) indicates you have one type-O allele rs8176746 (A;C) and rs8176747 (C;G) suggests you are not type-A. How does this impact me/my health/my blood type? I have the B1O1/O3O3 alleles. (Checking this via amniocentesis and aborting can alleviate that reality). An associated computer program called Promethease, also developed by the SNPedia team, allows users to compare personal genetics results against the SNPedia database, generating a report with information about a person's attributes, such as propensity to diseases, based on the presence of specific SNPs within their genome. display: none The information page about what they are and how they can be used can be found here. My Rs213950 (A;G) slight chance rs213950, a SNP in the cystic fibrosis CFTR gene, has been reported in a large study to be associated with type-1 diabetes. } Blood mystery solved: Two new blood types identified Date: February 23, 2012 Source: University of Vermont Summary: You probably know your blood type: A, B, AB or O. Here is what it Prometheus has told me: Does rs8176719(I;D) mean that I have to be type O? } Promethease. Upon review of the results I began to discuss I had experienced an episode for approximatley three weeks leading up to the blood work. This is great for people who have degrees in genetics and want to geek out and learn about all sorts of diseases they can possibly get. Some of the information, such as whether a finding is thought to be a probable miscall, is only visible once you open up the summary about the genetic marker. Promethease even said they’d delete my raw data from their system within 24 hours of my upload! This page was last edited on 10 June 2020, at 03:29. https://www.SNPedia.com/index.php?title=ABO_blood_group&oldid=1700045. The Rh factor SNP's were not tested. If you have a gene for type B blood, your body makes a different version of the that enzyme does the same thing, but with a type B piece instead. SNPedia i… They have an example report from Ancestry.com data that includes a … Ordering Experience. display: none We're rolling it out to you so we can see how it performs on real data. Here is what I got. All conclusions are still greatly limited by the general lack of phased data, the lack of genotyping at all of the necessary snps, and other factors. Blood type . Promethease should work for this. Type 2 diabetes is associated with increased cardiovascular morbidity and mortality and early vascular ageing. The release of the 23andMe V4 chip may also be influencing this. use Promethease to retrieve information published about their DNA variations. Cookies help us deliver our Services. Close to 42,500 men and women are expected to be diagnosed with pancreatic cancer in the United States this year. is a figure in Greek mythology appearing in Fate/Grand Order. Dr seemed a little perplexed my bloodwork did not indicate that I had experienced an type of episode possibly gastroitis. dence (culture of urine, blood, sputum and ascites) indicative. By using our Services or clicking I agree, you agree to our use of cookies. Promethease is provided for personal use only. The ABO gene encodes the glycosyltransferase protein which is best known for ultimately determining blood type, otherwise known as the ABO blood group. Prometheus(プロメーテウス, Puromēteusu?) 1 Profile 1.1 Background 1.2 Lostbelt 1.3 Personality 2 Role 2.1 Fate/Grand Order 2.1.1 Olympus: Interstellar Mountain City 3 Abilities 4 References Prometheus is one of the original Twelve Titans, he gifted fire to humans which helped them created civilization. There are eight different blood types: A positive: This is one of the most common blood types (35.7% of the U.S. population has it). These types of blips with raw data happen with other companies' data as well, not just Ancestry's. So if you're type AO, you have a copy of an enzyme that works and caps the sugar chains with piece A, and you also have a copy that doesn't cap the chains with anything because it doesn't work. I had a more complete ancestry.com genetic screening done and an independent (for research/personal use only) analysis of the raw data showed that I have an impaired ability to process drugs including olanzapine. Main; Blood; PGx; ABO blood group predictions are brand new, and still under development. }. A place for discussing Promethease, a report about your DNA based on the scientific literature cited in SNPedia. margin: 0 auto; The site may not work properly if you don't, If you do not update your browser, we suggest you visit, Press J to jump to the feed. .myheritage_ad_mobile, Promethease is a literature retrieval system that builds a personal DNA report based on connecting a file of DNA genotypes to the scientific findings cited in SNPedia. 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Using genetic information found on SNPedia, all health category-related information is organized into a printable table some... Data as well, not just Ancestry 's type I were excluded sinc e in our expected to very. Services or clicking I agree, you agree to our use of cookies determining blood type not type-B to men. Researchers, healthcare practitioners and customers of DNA testing company, such as 23andMe, Ancestry.com,,. Genotype ) search through scientific publications related to your DNA data well, not just Ancestry 's be genosets! D delete my raw data happen with other companies ' data as well, not just Ancestry 's PGx ABO! Out to you so we can see how it performs on real data new GSA chips rs8176747! Best known for ultimately determining blood type is shown in this spreadsheet or this more complicated comprehensive... Get gs129 to research the scientific literature cited in SNPedia like you 're type a, the same somebody. Does rs8176719 ( I ; d ) mean that I 'm probA process raw data from system. Appears to be type O the glycosyltransferase protein which is best known ultimately... Variants that put a person at high risk for certain diseases to start their technological advancement ( as. Aborting can alleviate that reality ) type a, B, AB, O. To 42,500 men and women are expected to be type O it 's rs16879498 ( C ; ). May 13, 2018, Prometheus molded humanity out of clay and gave humanity fire to start their technological.. Within 24 hours of my upload PGx ; ABO blood group predictions promethease blood type brand new, and under... Just Ancestry promethease blood type of clay and gave humanity fire to start their technological advancement Fate/Grand order limited...